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Intraductal tubulopapillary neoplasm
Catherine Yu1, Julie Lokan2, Louise Jackett2
1General Medicine, Austin Health, Melbourne, Victoria, Australia catherine.yu@austin.org.au.
BMJ Case Reports
|December 22, 2022
Summary
This case report details a rare intraductal tubulopapillary neoplasm (ITPN) in an elderly male with ulcerative colitis. The patient recovered well after surgical resection, highlighting ITPN as a diagnosis to consider for pancreatic masses.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Intraductal tubulopapillary neoplasm (ITPN) is a rare pancreatic duct tumor with poorly understood risk factors.
- Ulcerative colitis is an inflammatory bowel disease with potential associations with various cancers.
Observation:
- An elderly male patient with a history of ulcerative colitis presented with unintentional weight loss.
- Imaging revealed a pancreatic mass with pancreatic duct dilatation; initial biopsies were inconclusive.
- Histopathology and immunohistochemistry of a resected specimen confirmed the diagnosis of ITPN.
Findings:
- This is the first reported case of ITPN in a patient with ulcerative colitis.
- The patient experienced a favorable outcome with no recurrence two years post-surgery.
Implications:
- This case expands the understanding of ITPN presentation and potential associations.
- Highlights the importance of considering ITPN in the differential diagnosis of pancreatic masses, especially in patients with inflammatory conditions.
