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Updated: Aug 16, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Chronic oral diseases burden: The confluence of caries and periodontitis throughout life
Susilena Arouche Costa1,2, Cecilia Claudia Costa Ribeiro1,3, Fábio Renato Manzolli Leite2,4,5
1Graduate Program in Dentistry, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Aim:
To investigate the confluence of caries and periodontitis indicators from adolescence to elderhood among Americans.
Materials And Methods:
This cross-sectional study explored the grouping among a set of caries and periodontitis indicators (the proportion of sites with bleeding on probing, moderate probing pocket depth [PPD, 4-5 mm], severe PPD [≥6 mm], moderate clinical attachment level [CAL, 3-4 mm], severe CAL [≥5 mm], number of teeth with furcation involvement, number of decayed teeth, number of teeth with pulp involvement, and the number of missing teeth) in 14,421 Americans from the NHANES III study. Exploratory factorial analysis was used to determine the constructs between those indicators (factorial loading ≥0.3). These analyses were stratified by age and confirmed with a confirmatory factorial analysis. We also performed a sensitivity analysis using the NHANES 2011-2014.
Results:
Two constructs were extracted. The first, Chronic Oral Diseases Burden, grouped caries indicators with moderate PPD and moderate CAL for the youngest subjects (13-39 years old), while for the subjects over 50 years, the Chronic Oral Disease Burden grouped caries indicators with severe CAL and PPD and furcation involvement. The second construct, Periodontal Destruction, grouped only periodontitis indicators.
Conclusions:
Caries and periodontitis indicators grouped consistently across the different age ranges in lapse times of 25 years.
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