Related Experiment Video

Updated: Aug 16, 2025

Affinity Purification of Influenza Virus Ribonucleoprotein Complexes from the Chromatin of Infected Cells
11:20

Affinity Purification of Influenza Virus Ribonucleoprotein Complexes from the Chromatin of Infected Cells

Published on: June 3, 2012

13.2K

Polymeric Materials as Indispensable Tools to Fight RNA Viruses: SARS-CoV-2 and Influenza A

Ariana C F Santos1, Fátima Martel2,3, Carmen S R Freire1

  • 1CICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.

Bioengineering (Basel, Switzerland)
|December 23, 2022
PubMed

Insights

Polymeric materials offer versatile solutions for combating RNA viruses like COVID-19. This review highlights their crucial role in protection, detection, and treatment strategies against viral diseases.

Area of Science:

  • Materials Science
  • Virology
  • Public Health

Background:

  • The emergence of coronavirus disease 2019 (COVID-19) in late 2019 marked the beginning of a global pandemic.
  • Coronaviruses, like influenza A, are RNA viruses presenting similar infection symptoms.
  • Extensive research has been conducted to understand and combat this novel virus.

Purpose of the Study:

  • To review and highlight the application of polymeric materials in combating RNA viruses.
  • To explore the potential of polymers in various stages of viral disease management.
  • To emphasize the indispensable role of polymers in fighting viral pandemics.

Main Methods:

  • Appraisal of case studies focusing on polymeric materials.
  • Analysis of literature on polymer properties and applications in virology.
  • Review of research targeting protection, detection, and treatment of viral infections.

Main Results:

  • Polymeric materials demonstrate significant potential in antiviral applications.
  • Versatile features of polymers can be leveraged for protection against viral entry.
  • Polymers show promise in developing sensitive detection methods and effective treatment modalities.

Conclusions:

  • Polymeric materials are essential tools in the fight against RNA viruses, including coronaviruses.
  • Their application spans critical areas such as personal protective equipment, diagnostics, and therapeutics.
  • Further research into polymeric materials can lead to innovative solutions for pandemic preparedness and response.
Keywords:
COVID-19RNA virusesinfluenza Apolymeric materials

More Related Videos

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization05:23

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization

Published on: December 23, 2020

6.2K
High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses11:34

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

Published on: May 5, 2014

13.9K

Related Concept Videos

Viruses with RNA Genomes01:29

Viruses with RNA Genomes

RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
81
Leaky Scanning02:28

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
5.2K
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.7K
Size and Structure of Viral Genomes01:26

Size and Structure of Viral Genomes

Viral genomes exhibit remarkable diversity in size, structure, and composition, influencing their replication strategies and interactions with host cells. These genomes consist of either DNA or RNA and may be linear or circular. Additionally, they can be single-stranded or double-stranded, with each configuration affecting how the virus propagates within a host. RNA viruses, for instance, generally have smaller genomes than DNA viruses, a factor that contributes to their high mutation rates and...
98
Viral Mutations00:36

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.7K
Conjugated Proteins02:50

Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
18.4K