Delphi-Based Consensus on Interstitial Lung Disease Screening in Patients with Connective Tissue Diseases (Croatian...

Area of Science:

• Rheumatology
• Pulmonology
• Radiology

Background:

• Interstitial lung disease (ILD) is a severe manifestation of connective tissue disease (CTD).
• Early detection of CTD-ILD is crucial for patient prognosis.
• Current screening and diagnostic strategies require standardization.

Purpose of the Study:

• To establish a Croatian Delphi-based expert consensus for screening ILD in CTD patients.
• To develop evidence-based screening and monitoring algorithms for various CTDs.
• To facilitate early identification of at-risk individuals.

Main Methods:

• Systematic literature review on ILD risk factors, prevalence, diagnostics, and prognosis in specific CTDs.
• Delphi-based expert consensus development using online surveys.
• Formation of a multidisciplinary team (rheumatologists, pulmonologists, radiologists).

Main Results:

• Two consensus-based screening algorithms for CTD-ILD were developed.
• Recommended detection strategy includes pulmonary function testing and high-resolution computed tomography (HRCT) for specific CTDs (IIM, MCTD, SSc) and those with risk factors.
• Pulmonary function testing is recommended for newly diagnosed pSS, RA, and SLE.

Conclusions:

• The developed consensus provides a standardized approach to CTD-ILD screening in Croatia.
• Early identification and monitoring strategies are essential for managing this severe CTD manifestation.
• Multidisciplinary collaboration is key for optimal patient outcomes.