Related Experiment Video
Updated: Aug 16, 2025

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Is It Possible to Analyze Kidney Functions, Electrolytes and Volemia Using Artificial Intelligence?
Danijela Tasić1, Katarina Đorđević2, Slobodanka Galović2
1UCC Niš, Clinic of Nephrology, Medical Faculty, University of Niš, 18000 Niš, Serbia.
Artificial intelligence models can predict cardiorenal balance by analyzing electrolytes and volemia. This approach aids in identifying patients at risk for electrolyte disturbances and hypervolemia, improving preventative strategies.
Area of Science:
- Cardiorenal Medicine
- Artificial Intelligence in Healthcare
- Biomarker Discovery
Background:
- Current clinical markers fail to differentiate permanent renal function impairment.
- Assessing cardiorenal balance requires evaluating volemia, sodium, and potassium levels.
- Understanding electrolyte interdependence is crucial for patient management.
Purpose of the Study:
- To investigate volemia and electrolyte status in cardiorenal patients using AI.
- To analyze the relationship between B-type natriuretic peptide, electrolytes, and cardiac function.
- To develop a predictive model for identifying patients at risk of cardiorenal complications.
Main Methods:
- Utilized an adaptive neuro fuzzy inference system (ANFIS) algorithm.
- Analyzed five key variables: B-type natriuretic peptide, sodium, potassium, ejection fraction, and EPI creatinine-cystatin C.
- Employed random regression for prognostic biomarker identification.
Main Results:
- B-type natriuretic peptide significantly influenced ejection fraction.
- Elevated sodium (Na+) and potassium (K+) levels correlate with patient deterioration and vital endangerment.
- The AI model successfully identified prognostic biomarkers for risk prediction.
Conclusions:
- AI-driven analysis of volemia and electrolytes offers a superior approach to traditional diagnostics.
- The model aids in optimizing preventative strategies and intensive monitoring for at-risk patients.
- Accurate and rapid diagnostic interpretation facilitates better patient treatment planning.
Related Concept Videos
Acute Kidney Injury V: Interprofessional Care
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury I: Introduction
Chronic Kidney Disease III: Interprofessional Care
Internal Anatomy of the Kidney
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Imaging Studies I: Kidney, Ureter, and Bladder Studies

