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Diagnostic Validity and Reliability of Low-Dose Prospective ECG-Triggering Cardiac CT in Preoperative Assessment of
Yassir Edrees Almalki1, Mohammad Abd Alkhalik Basha2, Sharifa Khalid Alduraibi3
1Division of Radiology, Department of Internal Medicine, Medical College, Najran University, Najran 61441, Saudi Arabia.
Insights
Low-dose prospective ECG-gated cardiac CT (CCT) offers a reliable method for diagnosing complex congenital heart diseases (CHDs) preoperatively. This advanced imaging technique provides high accuracy with reduced radiation exposure, aiding in surgical planning.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Complex congenital heart diseases (CHDs) require precise preoperative evaluation.
- Minimizing radiation dose exposure is crucial, especially in pediatric patients.
- Cardiac CT (CCT) is a valuable tool for cardiac imaging.
Purpose of the Study:
- To assess the diagnostic validity and reliability of low-dose prospective ECG-gated CCT.
- To evaluate the effectiveness of this method in complex CHDs.
- To determine radiation dose metrics for this protocol.
Main Methods:
- Prospective study including 42 patients with complex CHDs.
- Low-dose prospective ECG-gated cardiac CT (CCT) performed preoperatively.
- Independent image interpretation by two radiologists, validated against post-operative data.
Main Results:
- Mean effective radiation dose was 0.58 ± 0.13 mSv.
- High diagnostic performance: sensitivity (92.6-95.6%), specificity (97-98%), and accuracy (95.2-97%).
- Good inter-reader agreement (κ = 0.74) for CCT interpretation.
Conclusions:
- Low-dose prospective ECG-gated CCT is a valid and reliable method for preoperative assessment of complex CHDs.
- This technique enables precise diagnosis with reduced radiation exposure.
- It is particularly useful for evaluating coronary arteries in pediatric patients with CHDs.
Abstract:
For the precise preoperative evaluation of complex congenital heart diseases (CHDs) with reduced radiation dose exposure, we assessed the diagnostic validity and reliability of low-dose prospective ECG-gated cardiac CT (CCT). Forty-two individuals with complex CHDs who underwent preoperative CCT as part of a prospective study were included. Each CCT image was examined independently by two radiologists. The primary reference for assessing the diagnostic validity of the CCT was the post-operative data. Infants and neonates were the most common age group suffering from complex CHDs. The mean volume of the CT dose index was 1.44 ± 0.47 mGy, the mean value of the dose-length product was 14.13 ± 5.4 mGy*cm, and the mean value of the effective radiation dose was 0.58 ± 0.13 mSv. The sensitivity, specificity, PPV, NPV, and accuracy of the low-dose prospective ECG-gated CCT for identifying complex CHDs were 95.6%, 98%, 97%, 97%, and 97% for reader 1 and 92.6%, 97%, 95.5%, 95.1%, and 95.2% for reader 2, respectively. The overall inter-reader agreement for interpreting the cardiac CCTs was good (κ = 0.74). According to the results of our investigation, low-dose prospective ECG-gated CCT is a useful and trustworthy method for assessing coronary arteries and making a precise preoperative diagnosis of complex CHDs.
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