Related Experiment Video
Updated: Aug 16, 2026
07:01
Impression Cytology of the Lid Wiper Area
Published on: August 9, 2016
Epithelioid and polygonal cells in histoid leprosy
1Regional Leprosy Training and Research Institute, Raipur.
Indian Journal of Leprosy
|April 1, 1987
Summary
Histoid leprosy, a rare form of leprosy, presents with distinct histological features. This study highlights the presence of epithelioid and polygonal cells, which are uncommon findings requiring further investigation.
Area of Science:
- Dermatology
- Pathology
- Infectious Diseases
Background:
- Histoid leprosy is a rare form of Mycobacterium leprae infection.
- Understanding its histological variations is crucial for diagnosis and management.
Purpose of the Study:
- To present the salient histological features of 36 histoid leprosy cases.
- To investigate the occurrence and significance of uncommon cellular components in histoid leprosy.
Main Methods:
- Histopathological examination of 36 cases of histoid leprosy.
- Identification and documentation of key histological features, including cellular morphology and tissue architecture.
Main Results:
- All cases exhibited typical histoid features: whorls, interlacing spindle cells, and histoid bacilli.
- Uncommon findings included pseudocapsules (6 cases), epithelioid cell islets (5 cases), and polygonal foamy macrophages (12 cases).
- Epithelioid cells and polygonal cells were notably rare, with absent or sparse acid-fast bacilli.
Conclusions:
- Histoid leprosy displays characteristic histological patterns.
- The rare presence of epithelioid and polygonal cells in histoid leprosy warrants further research into their clinical and pathological significance.
Related Concept Videos
01:23Epithelial Tissues and Their Functions
Epithelial tissues are large sheets of cells covering all of the surfaces of the body. These surfaces can be internal or external, for example, skin, airways, the digestive tract, the urinary system, and the reproductive system. Hollow organs and body cavities that do not connect to the body's exterior, including blood vessels and serous membranes, are lined by epithelial tissue known as the endothelium.
Epithelial tissues provide the body's first line of protection from physical, chemical, and...
Epithelial tissues provide the body's first line of protection from physical, chemical, and...
01:30Classification of Epithelial Tissues: Simple Epithelium
Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell.
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...
01:29Classification of Epithelial Tissues: Stratified Epithelium
Stratified epithelium consists of several stacked layers of cells. They provide the durability to withstand constant physical and chemical attacks. Stratified epithelium is named after the shape of the most apical layer of cells. Stratified squamous epithelium is the most common type found in the human body. In this tissue, the apical cells are squamous, whereas the basal layer contains either columnar or cuboidal cells. The basal cells divide to form new daughter cells, which gradually become...
01:20Classification of Epithelial Tissues: Glandular Epithelium
The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Multicellular glands are formed during early development when epithelial budding...
01:18Lymphoid Cells and Tissues
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
01:27Histology of the Small Intestine
The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...