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The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A
Carlo Bieńkowski1,2, Justyna D Kowalska1,2, Marcin Paciorek1,2
1Hospital for Infectious Diseases in Warsaw, 01-201 Warsaw, Poland.
Insights
Patients hospitalized with COVID-19 during Poland's third pandemic wave experienced more severe illness and worse outcomes, including higher rates of serious complications and death.
Area of Science:
- Infectious Diseases
- Epidemiology
- Public Health
Background:
- The first case of COVID-19 in Poland was reported on March 4, 2020.
- This study focuses on patients hospitalized at the Hospital for Infectious Diseases in Warsaw.
Purpose of the Study:
- To compare the clinical course and outcomes of COVID-19 patients across three pandemic waves.
- To analyze demographic and clinical data of hospitalized COVID-19 patients in Warsaw.
Main Methods:
- Retrospective analysis of 2138 COVID-19 patient records from March 2020 to November 2021.
- COVID-19 diagnosis confirmed via RT-PCR or antigen testing.
- Pandemic waves defined by case numbers and dynamics.
Main Results:
- The third wave cohort (n=2138) had lower oxygen saturation and higher oxygen supplementation needs.
- Increased incidence of pneumothorax, thromboembolic events, ICU admission, and mortality observed in the third wave.
- Majority of patients were male (57.8%), median age 65 years.
Conclusions:
- COVID-19 patients during the third wave in Warsaw faced a more severe disease course.
- Outcomes were poorer for patients hospitalized during the third pandemic wave.
Abstract:
Background: The first case of coronavirus disease 2019 (COVID-19) in Poland was reported on 4 March 2020. We aim to compare the clinical course and outcomes of patients hospitalized in the Hospital for Infectious Diseases in Warsaw due to COVID-19 during three pandemic waves. Materials and methods: The medical data were collected for all patients diagnosed with COVID-19 hospitalized in our hospital from 6 March 2020 till 30 November 2021. COVID-19 diagnosis was confirmed by nasopharyngeal swabs using real-time polymerase chain reaction assay (RT-PCR) or SARS-CoV-2 antigen test. COVID-19 waves were defined based on the number and dynamics of cases. Results: Altogether, 2138 patient medical records were analyzed. The majority of the cohort was male (1235/2138, 57.8%), and the median age was 65 years [IQR: 50−74 years]. Patients hospitalized during the third wave had lower oxygen saturation on admission (p < 0.001) and were more likely to receive oxygen supplementation (p < 0.001). Serious complications, including pneumothorax (p < 0.001) and thromboembolic complications (p < 0.001), intensive care unit admission (p = 0.034), and death (p = 0.003), occurred more often in patients of the third wave. Conclusions: During the third wave, patients in our cohort experienced a more severe course of the disease and poorer outcomes.
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