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Outcomes after Transcatheter Mitral Valve Implantation: A Literature Review

George Samanidis1, Meletios Kanakis2, Konstantinos Perreas1

  • 1Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, 356 Leoforos Syggrou, 17674 Athens, Greece.

Journal of Personalized Medicine
|December 23, 2022
PubMed

Insights

Transcatheter mitral valve replacement offers a promising alternative for patients with severe mitral valve disease and comorbidities, providing new therapeutic options beyond traditional surgery.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Mitral valve disease is a prevalent global health issue.
  • Surgical valve repair/replacement is standard for severe cases, but comorbidities often exclude patients.
  • Transcatheter mitral valve repair (e.g., MitraClip) and replacement are emerging options for high-risk patients.

Purpose of the Study:

  • To review current therapeutic options for advanced mitral valve disease.
  • To discuss transcatheter mitral valve replacement (TMVR) as an alternative for patients unsuitable for surgery.
  • To present short-term outcomes of TMVR.

Main Methods:

  • Review of existing literature on mitral valve disease treatments.
  • Discussion of transcatheter techniques including edge-to-edge repair and valve implantation.
  • Analysis of published short-term outcomes for transcatheter mitral valve replacement.

Main Results:

  • Transcatheter mitral valve repair offers options for patients with severe comorbidities.
  • Transcatheter mitral valve replacement shows promising short-term outcomes.
  • TMVR is a viable alternative for advanced native or prosthetic mitral valve disease.

Conclusions:

  • Transcatheter mitral valve interventions are expanding treatment possibilities.
  • TMVR presents a potentially effective option for complex mitral valve disease.
  • Further research is needed to establish long-term efficacy and safety of TMVR.

Keywords:
implantationmitral valvereplacementtranscatheter

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