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Related Concept Videos

Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

296
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
296

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Battery-Free Tattooing Mechanism-Based Functional Active Capsule Endoscopy.

Manh-Cuong Hoang1, Jong-Oh Park1, Jayoung Kim1

  • 1Korea Institute of Medical Microrobotics, Gwangju 61186, Republic of Korea.

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A new tattooing capsule endoscope (TCE) uses a magnetic system for precise submucosal ink delivery in the digestive tract. This novel device enables targeted lesion tattooing and potential drug delivery, advancing endoscopic capabilities.

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active capsule endoscopegastrointestinal tract diagnosistattooing function

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Area of Science:

  • Gastroenterology
  • Medical Devices
  • Robotics

Background:

  • Capsule endoscopy currently lacks active locomotion and targeted tissue interaction capabilities.
  • Submucosal injection is crucial for lesion marking and targeted therapy in the digestive tract.

Purpose of the Study:

  • To develop and evaluate a novel tattooing capsule endoscope (TCE) capable of active locomotion and submucosal ink delivery.
  • To demonstrate the feasibility of using a magnetic actuation system for precise targeting and injection within the digestive tract.

Main Methods:

  • A dual-function permanent magnet was integrated into the capsule endoscope for both locomotion and injection activation.
  • The capsule endoscope achieved 5 Degrees of Freedom (DOF) locomotion via interaction with an external controllable magnetic field.
  • A specialized mechanism utilizing the magnet was designed to activate a squeezing motion for liquid ejection.

Main Results:

  • The prototype TCE, measuring 12.5 mm x 34.6 mm, successfully navigated and delivered tattoo agent into porcine intestinal tissue ex vivo.
  • The magnetic locomotion system enabled controlled movement towards the target site.
  • The injection mechanism effectively ejected the tattooing agent into the submucosal layer.

Conclusions:

  • The developed tattooing capsule endoscope (TCE) demonstrates a viable approach for targeted submucosal delivery in the digestive tract.
  • This technology holds potential for lesion tattooing and future applications in endoscopic drug delivery.
  • The findings contribute to the advancement of functional capsule endoscope development.