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Towards a Harmonized Terminology: A Glossary for Biocide Susceptibility Testing
Szilvia Neuhaus1, Andrea T Feßler2,3, Ralf Dieckmann1
1German Federal Institute for Risk Assessment, 10589 Berlin, Germany.
Pathogens (Basel, Switzerland)
|December 23, 2022
Summary
The excessive use of biocides may contribute to antimicrobial resistance, but a lack of standardized testing hinders scientific consensus. Developing standardized biocide susceptibility testing (BST) is crucial for accurate data interpretation and resistance evaluation.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Disinfection is vital for reducing infection rates.
- Biocide exposure in bacteria is linked to adaptation and antimicrobial resistance.
- Current scientific consensus on biocide's role in multidrug resistance is lacking.
Purpose of the Study:
- To investigate criteria and terms used in biocide susceptibility testing (BST) of field isolates.
- To analyze existing reviews on altered biocide susceptibility.
- To highlight the need for standardization in BST.
Main Methods:
- Review of original studies on biocide susceptibility testing (BST).
- Analysis of reviews summarizing knowledge on altered biocide susceptibility.
- Comparison of BST data interpretation with antimicrobial susceptibility testing (AST).
Main Results:
- Significant diversity in criteria and terms for interpreting BST findings.
- Lack of uniform test procedures, interpretive criteria, and harmonized terms for BST.
- Urgent need for standardization in biocide resistance evaluation.
Conclusions:
- Standardization of biocide susceptibility testing (BST) is urgently required.
- Established concepts for antimicrobial susceptibility testing (AST) can serve as a model for BST.
- Adaptations are necessary to address specific needs for BST data evaluation to increase scientific awareness and acceptance.
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