Global Research Trend in Vaccine Design

Area of Science:

• * Bibliometrics and Scientometrics
• * Vaccinology and Immunology
• * Information Science

Background:

• * The field of vaccine design has experienced substantial growth, particularly in the last two decades.
• * Understanding the research landscape is crucial for advancing vaccine development strategies.

Purpose of the Study:

• * To conduct a bibliometric analysis and network visualization of vaccine design research.
• * To identify prolific authors, institutions, and highly cited publications in the field.
• * To map the intellectual structure and collaboration patterns in vaccine design literature.

Main Methods:

• * Bibliometric indicators and network visualization techniques were employed.
• * Data was retrieved from Scopus, encompassing 5379 documents published between 1983 and 2021.
• * VOS Viewer and RStudio were utilized for data visualization and analysis.

Main Results:

• * Significant increase in vaccine design literature over the past two decades, with 2020 being the most productive year (477 publications).
• * D.R. Burton identified as the most prolific author (86 publications, 18,449 citations); National Institute of Health (NIH) as the most productive organization (266 publications).
• * The article "Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae" was the most cited (1398 citations). Keyword analysis showed "vaccine" and "vaccine design" as most frequent.
• * Five distinct author collaboration clusters were identified.

Conclusions:

• * The study provides a comprehensive overview of the vaccine design research landscape.
• * Findings highlight key contributors and emerging trends, aiding future research endeavors.
• * The bibliometric mapping will assist scholars and professionals in medicine, health, and information science to navigate and contribute to vaccine design research.