Chaotic signatures in host-microbe interactions
Yehonatan Sella1, Nichole A Broderick2, Kaitlin Stouffer3
1Department of Systems and Computational Biology, Albert Einstein College of Medicine,1301 Morris Park Ave, Bronx, NY 10461, USA.
Biorxiv : the Preprint Server for Biology
|December 23, 2022
Summary
Researchers explored chaotic dynamics in host-microbe interactions using time-to-death data. Preliminary findings suggest chaotic signatures in model organisms, potentially impacting infectious disease understanding and experimental reproducibility.
Area of Science:
- Ecology and Evolutionary Biology
- Microbiology
- Complex Systems
Background:
- Host-microbe interactions are complex dynamical systems, crucial for understanding infectious diseases.
- Characterizing the dynamics (deterministic, stochastic, chaotic) of these interactions is essential but experimentally challenging.
- Time-to-death data is a common experimental outcome, yet internal dynamics remain hidden.
Conclusions:
- Time-to-death data may contain information about underlying chaotic dynamics in host-microbe systems.
- The findings suggest that chaos could play a role in host-microbe interactions, with implications for disease dynamics.
- Further research with enhanced datasets is required to validate the presence and impact of chaos in microbial pathogenesis.
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