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Extraction: Advanced Methods

Extraction: Advanced Methods

Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...

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Related Experiment Video

Updated: Aug 16, 2025

Apparatus for Harvesting Tissue Microcolumns

Apparatus for Harvesting Tissue Microcolumns

Published on: October 25, 2018

Comedone Extractor with Multiple Variable Sized Holes for Mass Comedone Extraction.

Sanjeev Gupta¹, Sunita Gupta², Ajinkya Vinayak Gujrathi¹

¹Department of Dermatology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, India.

Journal of Cutaneous and Aesthetic Surgery

|December 23, 2022

Summary

This study addresses limitations of conventional comedone extractors, which are unsuitable for large-scale or variable-sized comedone removal. A new approach was developed to overcome these issues for improved dermatological procedures.

Keywords:

Acne comedone customized comedone extractor extraction innovation molluscum surgery

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Last Updated: Aug 16, 2025

Apparatus for Harvesting Tissue Microcolumns

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Published on: October 25, 2018

Selective Harvesting of Marginating-hepatic Leukocytes

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Published on: July 21, 2016

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Area of Science:

Dermatology
Medical Device Engineering

Background:

Conventional comedone extractors feature limited single or dual holes of fixed/variable sizes.
These devices are inefficient for mass comedone extraction, especially with diverse comedone sizes.

Purpose of the Study:

To develop an improved comedone extractor overcoming limitations of conventional devices.
To enhance efficiency and versatility in comedone extraction procedures.

Main Methods:

Design and fabrication of a novel comedone extractor.
Testing of the new device for efficacy in mass and variable-sized comedone removal.

Main Results:

The developed extractor demonstrates suitability for mass comedone extraction.
The device effectively handles comedones of variable sizes, outperforming conventional tools.

Conclusions:

The novel comedone extractor offers a significant improvement over existing technologies.
This innovation facilitates more efficient and effective dermatological treatments for comedones.