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Thyroid liposarcoma: a case report
Maxime Gerard1, Alexander N Flaris1,2, Marco Demarchi1
1Service de chirurgie endocrinienne, Hôpital Lyon Sud, Pierre Bénite, France.
Innovative Surgical Sciences
|December 23, 2022
Summary
Thyroid liposarcoma is a rare tumor. This case report details a 60-year-old male with a large thyroid nodule, emphasizing the need for thorough workup and en bloc resection for this rare thyroid cancer.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Thyroid liposarcoma is an exceptionally rare malignancy.
- Limited literature exists, primarily comprising case reports and small case series.
Observation:
- A 60-year-old male presented with neck discomfort and a large left thyroid nodule.
- Imaging revealed a thyroid nodule and two fatty formations in the posterior mediastinum.
- MRI demonstrated a mixed lesion in the lower neck and upper chest.
Findings:
- The patient underwent extensive surgical resection, including thyroid lobectomy and isthmus resection with sternotomy.
- Pathological evaluation identified a grade II dedifferentiated liposarcoma with an inflammatory component.
- Surgical procedures included tracheal, laryngeal, and esophageal shaving.
Implications:
- Management of thyroid liposarcoma necessitates comprehensive diagnostic evaluation.
- En bloc resection is the recommended surgical approach for thyroid liposarcoma.
- Adjuvant radiation therapy decisions depend on specific histological findings.

