Related Experiment Video
Updated: Jul 16, 2026

08:12
Assessing Somatic Hypermutation in Ramos B Cells after Overexpression or Knockdown of Specific Genes
Published on: November 1, 2011
Hematologist Bracha Ramot (1927-2006): Between the bedside and the bench
Laura Veronica Grunseid1, Nurit Kirsh1
1The Biological Thought Program, The Open University of Israel, Ra'anana, Israel.
Journal of Medical Biography
|December 23, 2022
Summary
Bracha Ramot pioneered hematology in Israel, establishing a key institute and researching blood disorders. Her significant contributions earned her the prestigious Israel Prize in Medical Sciences.
Area of Science:
- Medical Sciences
- Hematology
- Oncology
Background:
- The establishment of the first medical school in Israel in 1949 marked a significant milestone.
- Bracha (Chweidan) Ramot was among the inaugural students, later specializing in internal medicine and hematology.
Purpose of the Study:
- To highlight the contributions of Bracha Ramot to the field of hematology in Israel.
- To detail her research on environmental and genetic factors influencing hematological conditions.
- To recognize her leadership in establishing and directing the Hematological Institute.
Main Methods:
- Biographical analysis of Bracha Ramot's career and achievements.
- Review of her research contributions in internal medicine and hematology.
- Documentation of her role in founding and leading a major hematological institute.
Main Results:
- Ramot became a central figure in Israeli hematology, founding the Hematological Institute at Tel-Hashomer hospital in 1958.
- Her research focused on coagulation factors, glucose metabolism disorders, leukemias, lymphomas, and Hodgkin's disease.
- She was awarded the Israel Prize in Medical Sciences in 2001 for her extraordinary achievements.
Conclusions:
- Bracha Ramot's career exemplifies overcoming personal challenges to achieve remarkable success in medicine and research.
- Her work significantly advanced the understanding and treatment of hematological conditions in Israel.
- She is recognized as a pioneering figure and "The Doyenne of Israeli Hematology".
Related Concept Videos
The Blood-brain Barrier
47.9K
Overview
47.9K
Bronsted-Lowry Acids and Bases
92.8K
The acid-base reaction class has been studied for quite some time. In 1680, Robert Boyle reported traits of acid solutions that included their ability to dissolve many substances, to change the colors of certain natural dyes, and to lose these traits after coming in contact with alkali (base) solutions. In the eighteenth century, it was recognized that acids have a sour taste, react with limestone to liberate a gaseous substance (now known to be CO2), and interact with alkalis to form neutral...
92.8K
Regulation of Hematopoietic Stem Cells
3.3K
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
3.3K
Bone Marrow Sampling and Transplants
387
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
387

