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Antibiotic prescriptions for child sinusitis varied between specialties after Finnish guidelines were updated in 2018
Matti Korppi1, Sauli Palmu1, Paula Heikkilä1
1Centre for Child, Adolescent, and Maternal Health Research, Tampere University Hospital and Tampere University, Faculty of Medicine and Health Technology, Tampere, Finland.
Insights
Antibiotic prescribing for childhood acute sinusitis in Finland remained around 40% post-guideline update. Physician specialty influenced antibiotic use and guideline adherence.
Area of Science:
- Pediatric infectious diseases
- Antimicrobial stewardship
- Health services research
Background:
- Acute sinusitis is a common childhood diagnosis.
- Antibiotic overuse contributes to antimicrobial resistance.
- Updated national guidelines aimed to optimize antibiotic prescribing for acute sinusitis.
Purpose of the Study:
- To evaluate antibiotic prescription patterns for acute sinusitis in Finnish children.
- To assess adherence to updated national guidelines.
- To compare prescribing practices before and after guideline implementation.
Main Methods:
- Retrospective analysis of antibiotic prescriptions for acute sinusitis in children (2-17 years).
- Data collected from a nationwide private outpatient clinic network (2014-2020).
- Comparison of prescribing before (2014-2017) and after (2018-2020) guideline updates.
Main Results:
- Antibiotics were prescribed in 37.9%-41.6% of cases annually.
- Amoxicillin and amoxicillin-clavulanic acid were the most common antibiotics.
- Macrolide use decreased by 38%, while guideline adherence varied by physician specialty.
Conclusions:
- Antibiotic prescribing rates for pediatric acute sinusitis remained consistent around 40%.
- Physician specialty significantly impacted prescribing frequency and guideline adherence.
- Further interventions may be needed to optimize antibiotic use.
Aim:
We evaluated antibiotic prescriptions issued for Finnish children with acute sinusitis by a nationwide private outpatient clinic network from 2014-2020. Data were compared before and after updated guidelines in 2018.
Methods:
The study comprised data on 45 296 children aged 2-17 years with acute sinusitis, namely diagnoses, ages, dates, the doctor's specialty and any antibiotics. We measured compliance with the updated 2018 Finnish guidelines, which recommended amoxicillin or amoxicillin-clavulanic acid for children under 12 years old, with doxycycline as an alternative for 12 years plus.
Results:
There were 6621-7585 visits per year for acute sinusitis in 2014-2019 and 2954 in 2020. Antibiotics were prescribed for 37.9%-41.6% of patients during the study years. Amoxicillin, including penicillin, accounted for 35.9% of prescriptions, followed by amoxicillin-clavulanic acid (26.9%). Macrolides accounted for 20.6% and, encouragingly, decreased by 38% from 2014-2019. Doxycycline accounted for 5.3%. Paediatricians, general practitioners (GPs) and ear, nose and throat specialists followed the guidelines in 75.1%, 73.8% and 66.7% of cases, respectively. GPs prescribed antibiotics more often than other physicians.
Conclusion:
Antibiotics were prescribed for about 40% of acute sinusitis visits by Finnish children from 2014-2019. Specialities differed with regard to prescribing rates and whether they followed the guidelines.
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