Increased risk of incident atrial fibrillation in young adults with mental disorders: A nationwide population-based

Hyun Jin Ahn1, So-Ryoung Lee1, Eue-Keun Choi2

  • 1Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

Heart Rhythm
|December 23, 2022
PubMed

Insights

Young adults with mental disorders face a significantly higher risk of developing atrial fibrillation (AF). Increased awareness and monitoring for AF in this population are crucial for early detection and management.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Mental disorders and cardiovascular diseases share complex links.
  • Limited data exists on the incidence of atrial fibrillation (AF) in individuals with mental health conditions.

Purpose of the Study:

  • To investigate the association between mental disorders and the risk of new-onset atrial fibrillation (AF).
  • To specifically examine this risk in young adults (aged 20-39).

Main Methods:

  • Utilized the Korean National Health Insurance Database (2009-2012).
  • Included young adults without prior AF, diagnosed with depression, insomnia, anxiety, bipolar disorder, or schizophrenia.
  • Monitored for new-onset AF during the follow-up period.

Main Results:

  • A cohort of over 6.5 million subjects was analyzed.
  • Individuals with mental disorders exhibited a higher incidence of AF compared to those without.
  • Mental disorders were independently associated with a 1.53-fold increased risk of AF (aHR 1.526).
  • Specific disorders like bipolar disorder and schizophrenia showed a 2-fold higher AF risk.

Conclusions:

  • Young adults with mental disorders have an elevated risk of incident AF.
  • Healthcare providers should consider AF screening in young adults diagnosed with mental health conditions.
Abstract

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