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Suicidal intoxication with mercury chloride
Sławomir Majdanik1, Barbara Potocka-Banaś1, Sebastian Glowinski2,3
1Department of Clinical and Forensic Toxicology, Pomeranian Medical University in Szczecin, Powstanców Wielkopolskich 72, 70-111, Szczecin, Poland.
Forensic Toxicology
|December 23, 2022
Summary
This case study details a fatal suicidal poisoning involving mercury chloride, a highly toxic metallic compound. Forensic analysis confirmed lethal mercury levels in the blood, highlighting the severe dangers of corrosive sublimate.
Area of Science:
- Forensic Toxicology
- Environmental Health
Background:
- Historical context of elemental metal poisoning and evolving diagnostic capabilities.
- Mercury's continued presence in various applications despite efforts toward elimination.
- Introduction to a specific case of suicidal poisoning involving mercury chloride (corrosive sublimate).
Observation:
- A patient presented with severe symptoms including epigastric pain, vomiting, cyanosis, tachycardia, tremors, respiratory distress, dysphagia, slurred speech, rales, and diarrhea.
- Inductively coupled plasma mass spectrometry (ICP-MS) detected lethal concentrations of mercury (191 mg/L antemortem, 147 mg/L postmortem).
- Autopsy revealed extensive thrombotic necrosis in internal organs.
Findings:
- Mercuric chloride has a low estimated human fatal dose (1-4 g).
- Toxic effects include corrosive injury, severe GI disturbances, acute renal failure, and circulatory collapse.
- The presented case underscores the significant toxicity and lethality of mercury chloride.
Implications:
- Highlights the critical need for accurate toxicological diagnostics in cases of suspected metal poisoning.
- Emphasizes the persistent risks associated with mercury compounds in both historical and contemporary contexts.
- Provides valuable data for forensic and toxicological practice regarding mercury chloride poisoning.
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