Isolation of Clostridium difficile from diarrhoea patients in Bangladesh

An attempt was made to detect Clostridium difficile and its toxin from the stools of 20 patients with antibiotic-associated diarrhoea (AAD), 35 with colitis, six with chronic diarrhoea and 300 with watery diarrhoea. Two toxigenic and three non-toxigenic strains were isolated from patients associated with antimicrobial therapy. All 300 stools from watery diarrhoea patients, not associated with antibiotics, were negative for Cl. difficile and its toxin. We conclude that Cl. difficile might be a cause of AAD in Bangladesh.