Assessing risks at 22-24 weeks gestation

A Aghababaie1, M Zeina2

  • 1Homerton Healthcare NHS Trust.

Insights

New UK guidance allows considering resuscitation for extremely premature infants (22-24 weeks gestational age) case-by-case. This presents complex ethical decisions regarding survival-focused versus comfort-focused care for neonates.

Area of Science:

  • Neonatal Medicine
  • Perinatal Care
  • Medical Ethics

Background:

  • The British Association of Perinatal Medicine (BAPM) issued new guidance in 2019.
  • This guidance permits considering resuscitation for extremely premature infants (EPI) between 22-24 weeks gestational age (GA) on a case-by-case basis in the UK.
  • This has created significant discussion and uncertainty within UK neonatal units.

Purpose of the Study:

  • To explore the implications of the 2019 BAPM guidance on neonatal care decisions.
  • To address the challenges in determining fetal viability and best interests for infants under 24 weeks GA.
  • To examine the ethical considerations surrounding survival-focused care (SFC) versus comfort-focused care (CFC).

Main Methods:

  • Qualitative analysis of the BAPM guidance framework.
  • Review of ethical considerations in neonatal resuscitation.
  • Discussion of clinical decision-making processes for extremely premature infants.

Main Results:

  • The BAPM guidance introduces a new framework for managing extremely premature infants.
  • Decisions regarding viability and the provision of SFC or CFC are complex.
  • Despite the framework, persistent uncertainty remains in clinical practice.

Conclusions:

  • The 2019 BAPM guidance marks a shift in managing extremely premature infants.
  • Ethical dilemmas persist regarding the balance between survival and comfort in neonatal care.
  • Further clarification and support are needed for clinicians navigating these complex decisions.