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Updated: Aug 16, 2025
Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
Published on: May 30, 2011
Quantitative analysis of pulmonary perfusion with dual-energy CT angiography: comparison of two quantification
Hye Ju Lee1, Mark Wanderley2, Vivian Cardinal da Silva Rubin2
1Department of Radiology, Hospital das Clinicas da Faculdade Medicina da Universidade de Sao Paulo, Sao Paulo, SP, Brazil. hyejulee@gmail.com.
Abstract:
The study aimed to evaluate a quantification method of pulmonary perfusion with Dual-Energy CT Angiography (DE-CTA) normalized by lung density in the prediction of outcome in acute pulmonary embolism (PE). In this prospective study with CTA scans acquired with different breathing protocols, two perfusion parameters were calculated: %PBV (relative value of PBV, expressed per unit volume) and PBVm (PBV normalized by lung density, expressed per unit mass). DE-CTA parameters were correlated with simplified pulmonary embolism severity index (sPESI) and with outcome groups, alone and in combinationwith tomographic right-to-left ventricular ratios (RV/LV). PBVm showed significant correlation with sPESI. PBVm presented higher accuracy than %PBV In the prediction of ICU admission or death in patients with PE, with the best performance when combined with RV/LV volumetric ratio.
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