Related Experiment Video
Updated: Aug 16, 2025

Author Spotlight: Unveiling the Potential of VSFG Microscopy in Studying Mesoscopically Heterogeneous Self-Assembled Structures
Published on: December 1, 2023
Overview of cocaine identification by vibrational spectroscopy and chemometrics
Danielle Kochenborger John1, Klester Dos Santos Souza1, Marco Flôres Ferrão2
1Instituto de Química, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9500, Porto Alegre, RS, Brazil.
Abstract:
The use of non-destructive forensic methods for cocaine identification is of outstanding importance, given the amount of samples seized. Techniques such as ATR-FTIR, Raman, and NIR spectroscopy have become alternatives to circumvent this problem, as they allow fast, cheap analysis, and enable the reanalysis of samples. When combined with chemometrics, these spectroscopic methods can be used to determine and quantify cocaine samples, meaning that the limitations of existing techniques can be overcome. This review article covers spectroscopic techniques for identifying cocaine in different forms and matrices, such as food and textiles, which are materials used for smuggling. The chemometric identification of cocaine in oral fluid and water is also discussed. In addition, vibrational spectroscopy techniques using portable equipment are described. This work seeks to evaluate the main chemometric applications of spectroscopic data and to find new perspectives on the identification of cocaine using chemometrics.
More Related Videos
09:46Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
Published on: August 19, 2013
05:29Profiling Volatile Compounds in Blackcurrant Fruit using Headspace Solid-Phase Microextraction Coupled to Gas Chromatography-Mass Spectrometry
Published on: June 9, 2021
Related Concept Videos
IR Spectroscopy: Molecular Vibration Overview
Stretching vibrations are vibrational motions that occur along the bond line, changing the bond length or distance between two bonded atoms. They are further distinguished as symmetric or asymmetric. In symmetric stretching, the...
Spectroscopy of Carboxylic Acid Derivatives
Raman Spectroscopy: Overview
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
Raman Spectroscopy Instrumentation: Overview
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
NMR Spectroscopy: Chemical Shift Overview
For instance, the proton...
Chromatographic Methods: Classification
Chromatographic techniques are typically named by...