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Sacral neuromodulation for overactive bladder using the InterStim and BetterStim systems.

Lingfeng Meng^1,2, Zijian Tian^1,2, Yaoguang Zhang^3,4

¹Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, No. 1 Da Hua Road, Dong Dan, Beijing, 100730, China.

Scientific Reports

|December 24, 2022

Summary

Both InterStim and BetterStim sacral neuromodulation systems effectively treat overactive bladder (OAB). While both improved symptoms, the InterStim system showed better results for dry OAB, and BetterStim for wet OAB, warranting further investigation.

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Area of Science:

Urology
Neurology
Medical Devices

Background:

Overactive bladder (OAB) significantly impacts quality of life.
Sacral neuromodulation (SNM) is a treatment option for OAB.
Comparing different SNM systems is crucial for optimizing patient care.

Purpose of the Study:

To compare the clinical outcomes of InterStim and BetterStim SNM systems in treating OAB.
To evaluate the efficacy of these systems based on voiding diaries and subjective scores.
To identify potential differences in effectiveness for different OAB subtypes.

Main Methods:

Retrospective analysis of a database for InterStim and a clinical trial for BetterStim.
Inclusion of 113 patients with OAB undergoing stage II SNM implantation.
Comparison of preoperative, post-stage I, and post-stage II outcomes using voiding diaries and subjective scores.

Main Results:

Both InterStim and BetterStim systems demonstrated significant improvements in OAB symptoms.
Urination frequency was higher in the BetterStim group during the experience period and follow-up.
While baseline quality of life scores differed, these differences diminished post-treatment.

Conclusions:

Both SNM systems are safe and effective for OAB treatment.
InterStim may offer advantages for patients with dry OAB.
BetterStim might be more suitable for patients with wet OAB, requiring further research.