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Updated: Aug 16, 2025

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates
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Artificial Intelligence in Neurosurgery: A Bibliometric Analysis.

Victor Gabriel El-Hajj1, Maria Gharios1, Erik Edström1

  • 1Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

World Neurosurgery
|December 25, 2022
PubMed
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This study examines the most influential research papers regarding the application of artificial intelligence in neurosurgery. By analyzing citation patterns, the authors identify key trends in authorship, geographic distribution, and publication timing to understand how these technologies are shaping the field.

Area of Science:

  • Neurosurgery outcomes research within artificial intelligence
  • Bibliometric analysis in medical informatics

Background:

No prior work had resolved the full scope of highly cited literature regarding machine learning applications in brain surgery. That uncertainty drove researchers to quantify the influence of specific publications. It was already known that technological progress historically drives surgical innovation. Prior research has shown that computational tools can assist clinicians with complex diagnostic tasks. This gap motivated a comprehensive review of the most impactful papers. Scholars have observed a surge in digital health research over the last decade. That trend necessitated a formal evaluation of the current knowledge base. No prior work had resolved the demographic and geographic distribution of these influential studies.

Purpose Of The Study:

The aim of this study is to evaluate the most influential literature regarding the integration of computational intelligence into neurosurgical practice. This investigation addresses the need to understand how digital tools are currently impacting clinical workflows. The researchers seek to identify trends in research output and authorship demographics. By analyzing citation patterns, they clarify which topics currently drive academic discourse. This work explores the geographic distribution of high-impact studies to assess global participation. The authors intend to highlight disparities in representation within the scientific community. This effort provides a foundation for future discussions on equitable technological advancement. The study ultimately maps the evolution of this rapidly growing field through quantitative metrics.

Keywords:
Artificial intelligenceBibliometric analysisGender gapNeurosurgeryWomen in neurosurgeryneurosurgerymachine learningcitation metricsdigital health

Frequently Asked Questions

The researchers propose that these tools assist with pattern recognition in complex datasets. This allows for improved patient selection, diagnostic accuracy, and outcome prediction compared to traditional manual methods.

The team utilized the Web of Science database to identify the 50 most-cited publications. They employed R software for statistical evaluation of citation counts, publication dates, and author demographics.

The authors note that the United States contributed 22 of the 50 papers. This geographic concentration is necessary to understand the current global distribution of digital surgical research.

The study uses citation counts as a proxy for scientific impact. This metric allows the researchers to rank the influence of various publications within the neurosurgical community.

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Main Methods:

The review approach involved a systematic search of the Web of Science database. Investigators identified the fifty most frequently referenced papers concerning computational surgical support. This search spanned from the inception of the database through July 2022. The team extracted metadata including publication year, country of origin, and author gender. They performed statistical calculations using the R programming environment. This process allowed for the quantification of citation trends and demographic patterns. The researchers focused exclusively on high-impact literature to ensure relevance. This methodology provided a structured overview of the current academic landscape.

Main Results:

Key findings from the literature indicate that the top-cited paper was a systematic review from 2018. The citation counts for the analyzed list ranged from 29 to 159. The mean citation frequency reached 51.9 with a standard deviation of 24.8. Most of these influential works appeared after 2015, accounting for 85% of the total. The United States led the list with 22 contributing articles. Female first and last authorship occurred in only 18% and 0% of cases, respectively. Despite this, the impact of work by female authors matched that of their male colleagues. The data confirms a striking dominance of research originating from developed countries.

Conclusions:

The authors suggest that the most cited papers demonstrate a clear concentration of research output within wealthy nations. This synthesis and implications framing indicates that global health equity remains a significant challenge for digital surgical tools. The researchers propose that female scholars produce work with impact levels comparable to their male counterparts. However, the data confirms a persistent gender gap in authorship representation. The review highlights that the majority of influential literature emerged after 2015. This observation suggests a rapid acceleration of interest in computational neurosurgical support. The team concludes that while these technologies show promise, current participation is not diverse. Future efforts should prioritize broader inclusion to ensure equitable development of these advanced systems.

The analysis identified a mean citation count of 51.9 per article. This measurement reveals the high level of academic attention directed toward computational neurosurgical research.

The researchers propose that the underrepresentation of female authors and developing nations limits the field. They suggest that addressing these disparities is vital for the future of global surgical health.