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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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COPD: Pathogenesis and Clinical Features01:20

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
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Reticular Dermis01:15

Reticular Dermis

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Psoriasiform Dermatitis in a COVID-19 Patient.

Marlyn Wu1, Shereen Teymour1, Robin Ashinoff1

  • 1Hackensack Meridian Palisades Medical Center, Palisades, NJ, USA.

Case Reports in Dermatological Medicine
|December 26, 2022
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Summary

This case report details a patient experiencing a psoriatic rash flare during COVID-19. Understanding the link between COVID-19 and psoriasiform lesions is vital for better patient outcomes.

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Immunology

Background:

  • Psoriasis is a chronic inflammatory skin condition affecting 2% of the global population.
  • The COVID-19 pandemic exacerbated psoriatic symptoms due to limited dermatological access and increased stress.
  • Psoriasiform lesions are skin manifestations that require careful differential diagnosis.

Observation:

  • A 52-year-old male presented with a diffuse rash preceding a positive COVID-19 test.
  • The patient's rash appeared on multiple body areas.
  • The case report includes clinical images and a review of similar dermatological presentations.

Findings:

  • The report explores potential causes for the patient's psoriasiform rash in the context of COVID-19.
  • A treatment plan for the patient's condition is discussed.
  • Literature review highlights the importance of differentiating systemic diseases presenting with similar cutaneous lesions.

Implications:

  • Accurate diagnosis of systemic manifestations linked to cutaneous lesions is crucial for dermatologists.
  • Further research is needed to understand the association between COVID-19 infection and psoriasiform lesions.
  • Improved understanding can enhance prognostic and therapeutic strategies for affected patients.