Related Experiment Video

Updated: Aug 16, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

33.5K

Sex differences in the association between blood pressure and atrial fibrillation: A case-control study

Xiexiong Zhao1, Qilun Feng1,2, Abdul Wahid1

  • 1Department of Cardiology, The Third Xiangya Hospital, Central South University, Changsha, China.

Frontiers in Cardiovascular Medicine
|December 26, 2022
PubMed

Insights

High blood pressure (HBP) significantly increases atrial fibrillation (AF) risk, especially in women. Achieving individualized blood pressure targets is crucial for preventing AF, particularly in female patients.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Atrial Fibrillation Studies

Background:

  • Hypertension (HBP) is a known risk factor for cardiovascular diseases.
  • Atrial fibrillation (AF) is a common arrhythmia with significant morbidity.
  • The interplay between HBP, AF, and patient sex requires further investigation.

Purpose of the Study:

  • To investigate the association between hypertension and atrial fibrillation.
  • To determine how hypertension control impacts atrial fibrillation risk.
  • To explore the influence of patient sex on the hypertension-atrial fibrillation relationship.

Main Methods:

  • A case-control study design was employed.
  • Patients were stratified by blood pressure levels and control status.
  • Logistic regression and propensity score matching were utilized to analyze odds ratios for AF by sex.

Main Results:

  • Hypertension, particularly higher grades, was strongly associated with increased AF risk (ORs ranging from 1.75 to 4.30).
  • The association between severe hypertension (grade 3) and AF was significantly higher in women (OR=7.15) compared to men (OR=2.48).
  • Uncontrolled hypertension showed a greater association with AF, especially in women (OR=3.09).
  • Specific blood pressure thresholds associated with increased AF risk were identified for men and women.
  • Lowering blood pressure to targeted levels was associated with reduced AF prevalence.

Conclusions:

  • A significant association exists between hypertension and atrial fibrillation, with a more pronounced relationship observed in female patients.
  • Individualized and potentially lower blood pressure targets may be beneficial for preventing atrial fibrillation in women.
  • Effective hypertension management is critical for reducing AF incidence.
Abstract

Keywords:
atrial fibrillationblood pressurecase control studyhypertensionsex differences

More Related Videos

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

1.8K
The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

83.8K

Related Concept Videos

Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
3.4K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
2.2K
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
1.2K
Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
613
Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
819
Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
793