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Disability and premorbid adjustment in schizophrenia: A retrospective analysis
Omokehinde O Fakorede1,2, Adegboyega Ogunwale1, Akinwande O Akinhanmi1
1Department of Clinical Services, Neuropsychiatric Hospital, Aro, Abeokuta, Nigeria.
Summary
Schizophrenia disability is linked to premorbid adjustment. Early identification of premorbid factors may help reduce future disability in schizophrenia patients.
Area of Science:
- Neuroscience
- Psychiatry
- Clinical Psychology
Background:
- Schizophrenia is a highly disabling mental illness.
- Predicting schizophrenia-related disability during the premorbid phase remains challenging.
- Identifying premorbid clinical markers could enable interventions to ameliorate disability.
Purpose of the Study:
- To investigate the relationship between schizophrenia-related disability and premorbid adjustment.
- To explore potential premorbid predictors of functional outcomes in schizophrenia.
Main Methods:
- A cross-sectional study was conducted at a Nigerian neuropsychiatric hospital.
- 300 patients diagnosed with schizophrenia (aged 18-64) were included.
- Spearman's correlation was used to analyze the association between disability and premorbid adjustment.
Main Results:
- The study found a weak, direct correlation between disability and premorbid adjustment (r = 0.130, p = 0.025).
- Mean participant age was 41.9 ± 10.05 years, with slight female predominance (50.7%).
Conclusions:
- Premorbid functioning may influence an individual's post-diagnosis functioning.
- Further research is needed to identify other premorbid factors for targeted prevention strategies.
- This study provides a foundation for early identification and intervention in schizophrenia.
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