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Updated: Aug 12, 2026

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
Published on: December 10, 2014
[Changes in regional and central hemodynamics during a 7-day immersion in water]
Abstract:
Regional and central hemodynamics were assessed at bi- and tetrapolar rheography and tacho-oscillography during 7-day "dry" immersion and 8-day -8 degrees head-down tilt. Blood redistribution evident from enhanced pulse filing of the brain, lungs and arms was most pronounced on day 3-5. The onset of the blood outflow to the liver was observed on immersion day 5 due to compensatory and adaptive reactions. Lack of exercise tolerance of cardiovascular system through its insufficient training was similar in the immersion and head-down tilt for all the 6 healthy males studied (aged 41-49) despite more obvious changes in regional hemodynamics during the immersion, which recovered on its fifth day.

