Related Experiment Video

Updated: Aug 16, 2025

Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
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Indication for tonsillectomy in pediatric patients with suspected post-transplant lymphoproliferative disorder

Juan P García Arteaga1, María S Cardozo1, Cecilia S Pastore1

  • 1Department of Ear, Nose and Throat, Hospital de Pediatría S.A.M.I.C. Prof. Dr. Juan P. Garrahan, City of Buenos Aires, Argentina.

Archivos Argentinos De Pediatria
|December 27, 2022
PubMed

Insights

Post-transplant lymphoproliferative disorders (PTLD) can affect palatine tonsils. This study details clinical features of pediatric transplant recipients who had tonsillectomies to diagnose PTLD, despite common tonsillar hypertrophy.

Area of Science:

  • Pediatric transplantation
  • Immunology
  • Oncology

Background:

  • Palatine tonsils are a frequent site for lymphoid hyperplasia in post-transplant lymphoproliferative disorders (PTLD).
  • Tonsillar hypertrophy is common in children, potentially masking PTLD and delaying diagnosis.
  • Early PTLD detection is crucial for patient outcomes in pediatric transplant recipients.

Keywords:
lymphoproliferative disordersorgan transplantationtonsillectomy

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