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An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
Endometrial cancer and obesity: Addressing the awkward silence
Lacey King1, Shilpa Gajarawala, Melissa D McCrary
1At the time this article was written, Lacey King was a student in the PA program at Emory University in Atlanta, Ga. She now practices at Emory University. Shilpa Gajarawala is a lead PA in the Department of Medical and Surgical Gynecology at the Mayo Clinic Florida in Jacksonville, an assistant professor of obstetrics and gynecology in the Mayo Clinic College of Medicine, and adjunct faculty in the doctor of medical science program at the Rocky Mountain University of Health Science in Provo, Utah. Melissa D. McCrary practices in hospital internal medicine at the Mayo Clinic Florida and is an instructor of obstetrics and gynecology at the Mayo Clinic College of Medicine and Science. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
Endometrial cancer is the most common malignancy of the female reproductive system diagnosed in the United States. The most commonly cited cause is unopposed endogenous estrogen produced by excess adipose tissue. Endometrial cancer typically is diagnosed in postmenopausal women with a body mass index (BMI) of 25 kg/m2 or more. This article reviews how clinicians can use a systematic approach to fill the awkward silence when talking with patients about weight. Meaningful conversations about weight loss can be achieved using the 5 A's for obesity management with the goal of decreasing diagnosis and increasing survivorship from endometrial cancer.
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