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Updated: Aug 16, 2025
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
[Use of optical coherence tomography in diagnosis of retinal lymphomas]
O F Tropinskaya1, N K Serova1, N M Eliseeva1
1N.N. Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia.
Abstract:
Primary intraocular lymphomas (PIOL) affecting the vitreoretinal complex is a rare nosology, and because of that PIOLs often cause diagnostic difficulties and/or lead to misdiagnosis. In the event of retinal lesions, in addition to routine ophthalmoscopy, optical coherence tomography (OCT) of the retina plays an important role in the diagnosis of the disease.
Purpose:
Evaluation of the characteristic features of retinal lymphomas using OCT.
Material And Methods:
The study included 6 patients (10 eyes) with retinal lymphomas associated with brain lesions of diffuse large B-cell lymphoma (DLBCL) who were treated at the N.N. Burdenko National Medical Research Center of Neurosurgery from 2017 to 2020; they were examined with OCT.
Results:
All patients with retinal lymphomas showed typical OCT signs in the form of hyperreflective subretinal infiltrates.
Conclusion:
OCT is a modern non-invasive method that allows diagnosing retinal lymphomas based on clinical and instrumental signs with a high degree of reliability.
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