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Published on: May 26, 2023
[Features of the course of lamellar macular holes with epiretinal proliferation]
K S Zhogolev1, Y V Bayborodov1,2, I E Panova1
1Saint Petersburg branch of S.N. Fedorov National Medical Research Center «MNTK «Eye Microsurgery», Saint Petersburg, Russia.
Abstract:
The question of the course of lamellar macular holes (LMH) - favorable or progressive - remains controversial to this day. It is important to study the features of the course of this pathology in patients with epiretinal proliferation (EP).
Purpose:
To establish the features of the course of lamellar macular holes with the presence of epiretinal proliferation.
Material And Methods:
Clinical and instrumental monitoring was carried out in 48 patients with LMH divided into two groups: with the presence of EP (n=27) and its absence (n=21). The follow-up period lasted 15.9±2.3 months. The following parameters were assessed: changes in best corrected visual acuity (BCVA), mean retinal sensitivity (MRS) of the retina in 2- and 4-degree zones, subjective complaints; the main morphometric and morphostructural parameters of the retina were evaluated using optical coherence tomography (OCT).
Results:
Patients with LMH and EP had lower initial BCVA, as well as, according to OCT, disruption of the ellipsoid zone and the presence of a foveal bump (37% and 22.2% of patients, respectively). During the follow-up, patients with EP showed an increase in subjective complaints, a statistically significant decrease in MRS in the 2-degree zone, and a decrease of the minimal retinal thickness.
Conclusion:
LMH with EP are characterized by an unfavorable course, which is confirmed by a decrease in functional and anatomical parameters.
