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Published on: August 11, 2023
Late-post-COVID-19 cerebral venous sinus thrombosis and stroke: a case report
Nino Cmor1, Eva Dora1, Darko Rajtman1
1Division of Cardiology.
Insights
Coronavirus disease 2019 (COVID-19) can lead to delayed cerebral venous sinus thrombosis (CVST) and stroke, even weeks after infection. This highlights a potential long-term complication requiring clinical vigilance.
Area of Science:
- Neurology
- Infectious Diseases
- Hematology
Background:
- Coronavirus disease 2019 (COVID-19) is associated with an increased risk of venous thromboembolisms (VTE), including deep vein thrombosis and pulmonary embolism.
- Cerebral venous sinus thrombosis (CVST) is a rare but serious complication linked to COVID-19, typically observed during the acute phase of the illness.
Observation:
- This report details a case of CVST and stroke occurring 56 days after a COVID-19 infection.
- The patient presented with an atypical clinical presentation, underscoring the varied manifestations of post-COVID-19 complications.
Findings:
- This case represents one of the first documented instances of CVST in the postacute phase of COVID-19.
- Persistent hypercoagulable conditions post-COVID-19 may contribute to late-onset VTE events.
Implications:
- Clinicians must consider CVST as a potential late complication in patients with a history of COVID-19.
- Awareness of this delayed risk necessitates the use of appropriate diagnostic imaging in evaluating patients with relevant symptoms post-COVID-19.
Introduction:
Coronavirus disease 2019 (COVID-19) disease increases risk of venous thromboembolisms (VTE), primarily deep vein thrombosis and pulmonary embolism. Only a few cases of cerebral venous sinus thrombosis (CVST) in association with a COVID-19 infection have been reported and are limited to acute COVID-19 disease. Hypercoagulable conditions persist in postacute COVID-19 disease, which carries an increased risk of VTE.
Case Presentation:
We report a case of CVST and stroke 56 days post-COVID-19 infection presenting with an atypical clinical picture.
Discussion:
To the best of our knowledge, this is one of the first observations of CVST in the postacute phase of COVID-19 disease. Clinicians should be aware of this potential late complication and should consider appropriate diagnostic imaging techniques in patients with COVID-19-infection history.
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