Late-post-COVID-19 cerebral venous sinus thrombosis and stroke: a case report

Nino Cmor1, Eva Dora1, Darko Rajtman1

  • 1Division of Cardiology.

Insights

Coronavirus disease 2019 (COVID-19) can lead to delayed cerebral venous sinus thrombosis (CVST) and stroke, even weeks after infection. This highlights a potential long-term complication requiring clinical vigilance.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Hematology

Background:

  • Coronavirus disease 2019 (COVID-19) is associated with an increased risk of venous thromboembolisms (VTE), including deep vein thrombosis and pulmonary embolism.
  • Cerebral venous sinus thrombosis (CVST) is a rare but serious complication linked to COVID-19, typically observed during the acute phase of the illness.

Observation:

  • This report details a case of CVST and stroke occurring 56 days after a COVID-19 infection.
  • The patient presented with an atypical clinical presentation, underscoring the varied manifestations of post-COVID-19 complications.

Findings:

  • This case represents one of the first documented instances of CVST in the postacute phase of COVID-19.
  • Persistent hypercoagulable conditions post-COVID-19 may contribute to late-onset VTE events.

Implications:

  • Clinicians must consider CVST as a potential late complication in patients with a history of COVID-19.
  • Awareness of this delayed risk necessitates the use of appropriate diagnostic imaging in evaluating patients with relevant symptoms post-COVID-19.
Abstract

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