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Activation of the alternative complement pathway by a streptococcal lipoteichoic acid
Infection and Immunity
|October 1, 1978
Abstract:
A glycerol lipoteichoic acid antigen from Streptococcus pyogenes 1-RP41 was found by rabbit erythrocyte hemolytic assay to activate the alternative complement pathway in human sera. Over a narrow concentration range of the teichoic acid, complement consumption was dose dependent, whereas at higher concentrations of the acid complement consumption could not be detected.