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Effects of age on apparent 31P spin-lattice relaxation times of rat brain phosphates
J A Stolk1, J I Olsen, D W Alderman
1Department of Medicinal Chemistry, University of Utah, Salt Lake City 84112.
Magnetic Resonance in Medicine
|July 1, 1987
Abstract:
Apparent 31P spin-lattice relaxation times have been measured in vivo for brain phosphates in young adult, mature adult, and aged rats at 4.7 T and 35 degrees C. Statistically significant differences were found for most phosphate species, except PCr and gamma-ATP, among the three age groups, particularly between the young and mature adults. Age-related changes in tissue composition and exchange reactions are discussed as possible contributors to these results.