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Predictors of mortality and ICU requirement in hospitalized COVID-19 patients with diabetes: A multicentre study

Md Asaduzzaman1, Mohammad Romel Bhuia2, Mohammad Zabed Jillul Bari3

  • 1Department of Medicine, Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh.

Nursing Open
|December 28, 2022
PubMed

Insights

Older age and low oxygen saturation predicted mortality and ICU needs in hospitalized COVID-19 patients with diabetes. Identifying these COVID-19 diabetes predictors can improve patient outcomes.

Area of Science:

  • Infectious Diseases
  • Endocrinology
  • Critical Care Medicine

Background:

  • Diabetes mellitus is a significant comorbidity associated with severe COVID-19 outcomes.
  • Understanding predictors of mortality and intensive care unit (ICU) needs in diabetic COVID-19 patients is crucial for resource allocation and clinical management.

Purpose of the Study:

  • To identify predictors of in-hospital mortality and ICU requirements among hospitalized patients with COVID-19 and diabetes.

Main Methods:

  • Retrospective cross-sectional study of 500 COVID-19 patients with diabetes hospitalized between October 2020 and February 2021.
  • Logistic regression analysis was employed to determine significant predictors for ICU admission and mortality.

Main Results:

  • 11% of patients died, and 24% required ICU support. Lymphopenia, thrombocytopenia, and leukocytosis were more prevalent in non-survivors.
  • Significant predictors of mortality included older age, neutrophil count, platelet count, and admission SpO2.
  • Older age, ischemic heart disease, WBC count, D-dimer, and admission SpO2 predicted ICU requirement.

Conclusions:

  • Older age, low admission SpO2, and specific hematological markers are key predictors of mortality and ICU needs in diabetic COVID-19 patients.
  • These findings highlight the importance of close monitoring and early intervention for high-risk diabetic individuals hospitalized with COVID-19.
Abstract

Keywords:
COVID-19DMICU requirementMortality

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