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Updated: Aug 16, 2025

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
Published on: May 10, 2019
ABO blood group and cochlear function: evidence from a large sample size study
Changgeng Mo1, Ting Fung Ma2, Bradley McPherson1
1Human Communication, Development and Information Sciences, Faculty of Education, University of Hong Kong, Hong Kong SAR, China.
Objective:
The present study investigated the effect of blood group on cochlear function in a large participant sample across different age groups. The study hypothesis was that participants with blood group O would show relatively reduced cochlear function as reflected in otoacoustic emission (OAE) measures.
Design:
Data were collected from transient evoked otoacoustic emission (TEOAE), distortion product otoacoustic emission (DPOAE), DPOAE input/output (I/O) function, and spontaneous otoacoustic emission (SOAE) recordings.
Study Sample:
Four hundred and sixty-three normal hearing adults aged 20-59 years among the four ABO blood groups participated in the study.
Results:
TEOAE and DPOAE amplitudes did not reveal significant differences for participants with blood group O compared with participants with non-O blood groups. No significant differences in I/O function categories were found among participants with different blood groups. SOAE prevalence was also not significantly different across blood groups. However, previously reported age and gender differences for OAE variables were confirmed.
Conclusions:
Participants with blood group O were not found to have significantly reduced cochlear function, based on OAE measures. Results from the current study do not support the hypothesis that normal hearing individuals with different ABO blood groups differ in level of cochlear function.
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