Related Experiment Video
Updated: Aug 15, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Structural racism is associated with adverse postnatal outcomes among Black preterm infants
Kayla L Karvonen1,2, Safyer McKenzie-Sampson3,4, Rebecca J Baer3,5
1Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA. kayla.karvonen@ucsf.edu.
Insights
Structural racism, measured by segregation, is linked to worse health outcomes for Black preterm infants after hospital discharge. This includes more frequent acute care visits, readmissions, and deaths in the first year of life.
Area of Science:
- Public Health
- Sociology
- Neonatal Medicine
Background:
- Structural racism is a known contributor to racial disparities in perinatal health outcomes.
- Racial and income segregation are key indicators of structural racism.
- Adverse outcomes for Black preterm infants postnatally are a significant public health concern.
Purpose of the Study:
- To investigate the association between structural racism and adverse postnatal outcomes in Black preterm infants.
- To quantify the impact of racial and income segregation on the health of Black preterm infants after hospital discharge.
Main Methods:
- An observational cohort study of 13,321 Black birthing people delivering preterm infants in California (2011-2017).
- Utilized statewide birth cohort data and American Community Survey data.
- Quantified racial and income segregation using Index of Concentration at the Extremes (ICE) scores.
- Employed multivariable generalized estimating equations to assess associations between ICE scores and adverse postnatal outcomes (acute care visits, readmissions, death).
Main Results:
- Black birthing people in the least privileged ICE tertiles had infants with higher rates of frequent acute care visits (cRR 1.3), readmissions (cRR 1.1), and post-discharge death (cRR 1.9) in the first year.
- These associations remained significant after adjusting for infant and birthing person characteristics.
- Findings highlight the detrimental impact of segregation on infant health outcomes.
Conclusions:
- Structural racism, as indicated by racial and income segregation, is associated with adverse postnatal outcomes for Black preterm infants.
- These disparities persist beyond the perinatal period, impacting infant health after hospital discharge.
- Addressing structural racism is crucial for reducing racial disparities in postnatal outcomes for preterm infants.
Background:
Structural racism contributes to racial disparities in adverse perinatal outcomes. We sought to determine if structural racism is associated with adverse outcomes among Black preterm infants postnatally.
Methods:
Observational cohort study of 13,321 Black birthing people who delivered preterm (gestational age 22-36 weeks) in California in 2011-2017 using a statewide birth cohort database and the American Community Survey. Racial and income segregation was quantified by the Index of Concentration at the Extremes (ICE) scores. Multivariable generalized estimating equations regression models were fit to test the association between ICE scores and adverse postnatal outcomes: frequent acute care visits, readmissions, and pre- and post-discharge death, adjusting for infant and birthing person characteristics and social factors.
Results:
Black birthing people who delivered preterm in the least privileged ICE tertiles were more likely to have infants who experienced frequent acute care visits (crude risk ratio [cRR] 1.3 95% CI 1.2-1.4), readmissions (cRR 1.1 95% CI 1.0-1.2), and post-discharge death (cRR 1.9 95% CI 1.2-3.1) in their first year compared to those in the privileged tertile. Results did not differ significantly after adjusting for infant or birthing person characteristics.
Conclusion:
Structural racism contributes to adverse outcomes for Black preterm infants after hospital discharge.
Impact Statement:
Structural racism, measured by racial and income segregation, was associated with adverse postnatal outcomes among Black preterm infants including frequent acute care visits, rehospitalizations, and death after hospital discharge. This study extends our understanding of the impact of structural racism on the health of Black preterm infants beyond the perinatal period and provides reinforcement to the concept of structural racism contributing to racial disparities in poor postnatal outcomes for preterm infants. Identifying structural racism as a primary cause of racial disparities in the postnatal period is necessary to prioritize and implement appropriate structural interventions to improve outcomes.
More Related Videos
Related Concept Videos
Teratogenicity
Regression Toward the Mean
Stereotypes, Prejudice, and Discrimination
The Nativist Approach
Rh Blood Group
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...

