Single coronary ostium with obstructive hypertrophic cardiomyopathy treated using the Morrow procedure: a case report
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Updated: Aug 15, 2025

Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy
Published on: September 9, 2020
Xin Lv1, Jianhua Li1, Chuanzhen Liu1,2,3
1Department of Cardiovascular Surgery, Qilu Hospital of Shandong University, No.107, West Wenhua Road, Jinan, 250012, Shandong, China.
Insights
This study reports the first successful Morrow procedure for severe hypertrophic obstructive cardiomyopathy (HOCM) in a patient with a rare single coronary artery (SCA). Myocardial protection via antegrade perfusion proved safe in this unique case.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Cardiac Surgery
Background:
- Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac condition.
- Single coronary artery (SCA) is a rare congenital anomaly.
- Concomitant severe hypertrophic obstructive cardiomyopathy (HOCM) and SCA is exceptionally rare.
Observation:
- A 64-year-old female presented with severe HOCM and a single left coronary artery.
- The patient underwent surgical treatment for HOCM using the Morrow procedure.
Findings:
- This is the first reported case of HOCM with SCA treated surgically with the Morrow procedure.
- Antegrade perfusion for myocardial protection was safely administered during the procedure.
Implications:
- The Morrow procedure is a viable surgical option for HOCM even in the presence of SCA.
- Safe myocardial protection strategies are crucial for patients with complex coronary anomalies and HOCM.
Background:
Hypertrophic cardiomyopathy is a commonly inherited heart disease. In addition, single coronary artery (SCA) is a rare congenital anomaly of the coronary arteries. And SCA concomitant with severe hypertrophic obstructive cardiomyopathy (HOCM) has seldom been reported in the literature. However, such cases have not been reported to be treated with the Morrow procedure.
Case Presentation:
Herein, we presented a case of a 64-year-old female diagnosed with a single left coronary artery with severe HOCM. The HOCM was treated with the Morrow procedure. The patient was discharged on the seventh postoperative day and was asymptomatic during the follow-up.
Conclusion:
To our knowledge, this is the first study reporting a single left coronary artery with severe HOCM treated with the Morrow procedure. In addition, myocardial protection by cardioplegia antegrade perfusion was safe for the patient with SCA and HOCM.
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