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Updated: Aug 15, 2025

Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers
Published on: October 17, 2013
Modelling of transport processes: Theory and simulations
Ankita Gupta1, Bipasha Pal1, Akriti Jindal2
1Department of Mathematics, Indian Institute of Technology, Ropar Rupnagar-140001, Punjab, India.
Abstract:
The transport processes, being a non-equilibrium system, have been a point of interest for physicists since many years revealing and explaining several unexpected effects. Such systems are often dealt with an archetypal model, known as totally asymmetric simple exclusion process, with two different types of boundary conditions: open and periodic. Moreover, these models are analyzed in two varieties of dynamics, random sequential and parallel updates, even at the micro level which play an important role in the global dynamics of the system. On contrary to the random sequential rule, the parallel updates introduce correlations in the system. Using theoretical and numerical methods in the framework based on mean-field approaches, the system properties are analyzed in both transient and steady state.•Both the updating rules are realized using Monte Carlo simulations.•In simplest form, mean-field approach ignores all the correlations and the results coincide with the random sequential update.•Correlations are induced in the system due to parallel update, therefore, a cluster mean-field theory is also discussed to handle them.
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