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Updated: Aug 15, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasis in Pediatric Age Group
Sandipan Dhar1, Sahana M Srinivas2
1Departments of Pediatric Dermatology, Institute of Child Health, Kolkata, West Bengal, India.
Insights
Childhood psoriasis, an immune-mediated inflammatory disease, impacts children and families. Proactive therapy offers a new approach to manage pediatric psoriasis and improve quality of life.
Area of Science:
- Dermatology
- Immunology
- Pediatrics
Background:
- Psoriasis is a chronic, immune-mediated inflammatory disease affecting all ages.
- Childhood-onset psoriasis impacts quality of life for children and families.
- Chronic plaque psoriasis is the most common type in children.
Purpose of the Study:
- To describe the distinct clinical presentations of pediatric psoriasis.
- To highlight the challenges in managing childhood psoriasis.
- To introduce proactive therapy as a potential management strategy.
Main Methods:
- Review of existing literature on pediatric psoriasis.
- Analysis of clinical presentations and comorbidities.
- Evaluation of 'proactive therapy' approach.
Main Results:
- Pediatric psoriasis presents with smaller, less pruritic plaques, often violaceous or hyperpigmented in darker skin.
- Associated comorbidities include arthritis, metabolic syndrome, depression, and anxiety.
- Management is challenging due to limited approved therapies.
Conclusions:
- Routine screening for comorbidities in pediatric psoriasis is essential.
- 'Proactive therapy' may help prevent flare-up severity and improve quality of life.
- Further research into pediatric psoriasis management is warranted.
Abstract:
Psoriasis is a common, chronic, immune-mediated, multisystem, inflammatory disorder. It affects all age groups, including infancy. In one-third of the cases, the onset of the disease is in the first and second decades of life. Childhood psoriasis significantly affects the quality of life of the child as well as that of the entire family. Pediatric psoriasis has distinct clinical presentations and evolves with time. Like in adults, chronic plaque psoriasis has been found to be the most common type of childhood psoriasis. Psoriatic plaques in children are less pruritic, smaller and thinner with less prominent scaling. In pigmented skin, the erythema is less prominent and plaques appear violaceous or hyperpigmented. Pediatric psoriasis can be associated with arthritis, metabolic syndrome, depression and anxiety. Hence all children should be screened routinely for associated comorbidities. Management of pediatric psoriasis is challenging owing to the limitation of approved therapies. 'Proactive therapy' is a recent approach in childhood-onset psoriasis that would help to prevent the severity of flare-ups, thus improving the quality of life.
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