Gender Difference in Cognitive Function Among Stable Schizophrenia: A Network Perspective
Mengyi Chen1, Lei Zhang1, Qi Jiang1
1Department of Geriatric, Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, Shanghai, People's Republic of China.
Neuropsychiatric Disease and Treatment
|December 29, 2022
Summary
Cognitive function in schizophrenia shows no significant gender differences. However, language is key for males, while delayed memory is central for females with schizophrenia.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Psychology
Background:
- Schizophrenia significantly impacts cognitive function, affecting daily living.
- Understanding gender-specific cognitive profiles in schizophrenia is crucial for targeted interventions.
Purpose of the Study:
- To examine gender-based differences in cognitive function among stable schizophrenia patients.
- To identify factors influencing cognition and explore distinct cognitive characteristics in male and female patients.
Main Methods:
- 298 chronic schizophrenia patients were grouped by gender.
- Cognitive function assessed using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).
- Demographic, clinical characteristics, and network analysis were employed.
Main Results:
- No significant differences in overall or sub-item RBANS scores between genders.
- Cognitive function correlated with age, illness duration, age at onset, and PANSS scores differently in males and females.
- Network analysis revealed language as the core cognitive function for males and delayed memory for females.
Conclusions:
- Cognitive function scores in stable schizophrenia patients do not significantly differ by gender.
- Language and delayed memory emerge as core cognitive domains for males and females with schizophrenia, respectively.
More Related Videos
Related Concept Videos
01:30Negative and Cognitive Symptoms of Schizophrenia
108
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
108
01:29Biological Causes of Schizophrenia
115
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
115
01:17Schizophrenia
185
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
185
01:29Psychological and Sociocultural Causes of Schizophrenia
160
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
160
02:12Relationship Formation
40.3K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
40.3K
01:27Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
842
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
842