Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gnotobiotes in nutritional studies.

M E Coates1

  • 1University of Reading, National Institute of Research in Dairying, Shinfield, England.

Die Nahrung
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

The gut microflora extensively synthesizes vitamins and modifies lipids, but its impact on host nutrition is minor. Its primary role is acting as a protective barrier against harmful organisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sulphonamides and potato starch refection in the rat.

Nature·2010
Same author

Some observations on perosis in chicks.

The Journal of comparative pathology and therapeutics·2010
Same author

A study of the composition of sow's milk.

The British journal of nutrition·2010
Same author

Interrelationships between the gastrointestinal microflora and non-nutrient components of the diet.

Nutrition research reviews·2008
Same author

Microbial amino acid synthesis and utilization in rats: incorporation of 15N from 15NH4Cl into lysine in the tissues of germ-free and conventional rats.

The British journal of nutrition·1996
Same author

A study of low-nutrient diets used for aging studies in the rat.

The journals of gerontology. Series A, Biological sciences and medical sciences·1996

Area of Science:

  • Microbiology
  • Human Physiology
  • Nutrition Science

Background:

  • The conventional gut microflora exhibits diverse metabolic activities, including vitamin synthesis, nitrogen metabolism, and lipid modification.
  • The host's physiological factors, such as gut structure and nutritional status, influence the extent of microflora activity.
  • Findings from gnotobiotic animal studies may not always directly translate to human physiology.

Purpose of the Study:

  • To evaluate the significance of indigenous gut microflora activities on host nutrition.
  • To compare the nutritional impact of gut microflora with its role as a protective barrier.

Main Methods:

  • Review of studies involving gnotobiotic animals.
  • Analysis of factors influencing microflora-host interactions.

Related Experiment Videos

  • Assessment of bacterial activity under varying dietary conditions.

    • Main Results:

    • Gut microflora demonstrates extensive vitamin synthesis, nitrogen compound metabolism, and lipid modification.
    • Microflora's influence on host nutrition can be detrimental or beneficial, particularly in dietary inadequacy.
    • These nutritional effects are generally small in magnitude.

    Conclusions:

    • The indigenous gut microflora's role in host nutrition is of relatively minor importance.
    • The primary significance of the gut microflora lies in its function as a barrier against pathogenic organism invasion.