Related Experiment Video
Updated: Aug 15, 2025

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
Anticoagulation During Pregnancy with a Mechanical Pulmonary Valve: Patient and Medical Perspective
Lauren Ledingham1, Amanda Thiess2, May Ling Mah3
1Heart Center, Nationwide Children's Hospital, Columbus, OH, USA. ledi05@osumc.edu.
Abstract:
This article discusses the challenges of supporting a successful pregnancy in a woman with multiple prosthetic heart valves and a complicated cardiac history, from both the patient and provider perspective. The patient is a 29-year-old female with truncus arteriosus type I with initial neonatal VSD closure and right ventricular to pulmonary artery conduit. At the age of 13, she subsequently required truncal and pulmonary valve replacements with mechanical prostheses. Standardizing an approach to anticoagulation in pregnancy in women with prosthetic heart valves is not always possible. Her story demonstrates the importance of an innovative approach to unique cases; by extrapolating what is known about pregnancy and prosthetic heart valves, cardiologists can provide the best outcomes. Simultaneously, non-directive counseling is essential throughout this period to engage the patient in shared decision-making when balancing risks and benefits of each approach to anticoagulation.
Related Concept Videos
Mitral Valve Prolapse III: Nursing Management
Mitral Valve Prolapse II: Assessment and Management
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Mitral Stenosis III: Medical Management
Venous Thrombosis III: Interprofessional Care
Mitral Regurgitation III: Medical Management

