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Granular cell tumour in the ciliary body
Yoshiharu Takeda1, Toshikatsu Kaburaki2, Akihiro Kakehashi1
1Department of Ophthalmology, Jichi Ika Daigaku Fuzoku Saitama Iryo Center, Saitama, Japan.
BMJ Case Reports
|December 29, 2022
Summary
This study presents a rare case of intraocular granular cell tumour (GCT) in the ciliary body. Early diagnosis and surgical intervention led to a favorable long-term outcome, highlighting GCT as a differential diagnosis for ciliary tumours.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Granular cell tumours (GCTs) are uncommon neoplasms, rarely occurring in intraocular locations.
- Intraocular GCTs require consideration in the differential diagnosis of ciliary body masses.
Observation:
- A rare case of intraocular GCT in the ciliary body of a young woman with a history of bone marrow transplantation is detailed.
- The tumour presented as a yellowish-white mass in the temporal periphery of the left eye.
- The patient also had bilateral proliferative diabetic retinopathy.
Findings:
- Surgical resection of the ciliary tumour was performed, combined with vitrectomy, silicone oil tamponade, and cataract surgery.
- Histopathological examination confirmed the diagnosis of ciliary GCT, characterized by specific cellular morphology.
- Immunohistochemical staining was positive for S-100 and vimentin, supporting the GCT diagnosis.
Implications:
- This case underscores the importance of considering intraocular GCT in the differential diagnosis of ciliary body tumours.
- Successful surgical management and long-term follow-up demonstrated no recurrence or complications.
- Further research may elucidate the specific etiology and optimal management strategies for intraocular GCTs.
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