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[Penbutolol and arterial hypertension]
A Torriani1, M Bravi, M Broglia
1Università di Pavia, Dipartimento di Medicina Interna e Terapia Medica.
Minerva Medica
|September 30, 1987
Summary
Penbutolol is an effective long-term treatment for hypertension, particularly hyperkinetic forms. It offers a good therapeutic response with minimal side effects and can be combined with other drugs for stubborn cases.
Area of Science:
- Pharmacology
- Cardiovascular Medicine
Context:
- Hypertension management
- Hyperkinetic hypertension treatment
Purpose:
- Evaluate penbutolol's efficacy and tolerability in hypertension treatment
- Assess its suitability for long-term use and combination therapy
Summary:
- Penbutolol demonstrates significant effectiveness in treating recent-onset hypertension, especially hyperkinetic types.
- The drug is well-tolerated, shows minimal side effects, and provides a rapid therapeutic response.
- It can be safely combined with dihydralazine, reserpine, and dihydrochlorothiazide for refractory hypertension, allowing reduced dosages of other agents without inducing bradycardia.
Impact:
- Provides a well-tolerated, effective therapeutic option for hypertension.
- Offers a viable strategy for managing complex and stubborn hypertension cases.
- Supports combination therapy approaches in cardiovascular pharmacotherapy.