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Commentary on "Antigen Retrieval Immunohistochemistry: Past, Present, and Future"

Clive R Taylor1, Shan-Rong Shi2

  • 1Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California.

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
|December 30, 2022
PubMed
Summary

No abstract available in PubMed .

Keywords:
FFPE tissueshybridoma techniqueperoxidase labeled antibodies

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Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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