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In vitro autoradiography of [3H]acetylcholine binding in rat hind limb muscles
1Department of Neurology, Uppsala University, Sweden.
Neuroscience Letters
|August 31, 1987
Abstract:
The morphological distribution of acetylcholine receptors in normal and denervated rat tibialis anterior and soleus muscles was studied by in vitro quantitative autoradiography with [3H]acetylcholine (ACh). In normal muscles [3H]ACh binding was restricted to the neuromuscular junction, while denervated muscles showed binding also in extrajunctional areas. After denervation there was also an increase in the junctional binding.