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Related Experiment Video

Updated: Aug 15, 2025

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Wellens Syndrome: A Possible Precursor.

Okelue E Okobi^1,2, Ibrahim O Bakare³, Endurance O Evbayekha⁴

¹Family Medicine, Arizona State University, Tempe, USA.

|December 30, 2022

Summary

This summary is machine-generated.

Wellens syndrome, an ECG pattern indicating critical LAD stenosis, requires urgent intervention. Recognizing this precursor to myocardial infarction is vital for emergency physicians to prevent adverse cardiac events.

Keywords:

critical care cardiology ecg interpretation ekg abnormalities electrocardiography (ecg)wellens’ syndrome

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Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

Area of Science:

Cardiology
Emergency Medicine
Diagnostic Electrocardiography

Background:

Wellens syndrome is a critical indicator of proximal left anterior descending (LAD) coronary artery stenosis.
It presents with specific electrocardiogram (ECG) findings: biphasic T waves (Type A) or inverted deep T waves (Type B) in precordial leads.
Early recognition by frontline clinicians is essential for timely intervention and improved patient outcomes.

Observation:

A clinical case involving Wellens syndrome with deep T waves in leads V2-V3 is presented.
This patient also presented with concurrent COVID-19 pneumonia, pleural effusions, and congestive heart failure.
The ECG findings were indicative of significant LAD coronary stenosis.

Findings:

The patient exhibited Type B Wellens syndrome ECG changes (deep, inverted T waves in V2-V3).
The clinical presentation was complicated by severe respiratory and cardiac compromise due to COVID-19.
Despite initial presentation, the underlying coronary stenosis led to a rapid and massive myocardial infarction.

Implications:

Failure to diagnose Wellens syndrome can lead to catastrophic outcomes, including myocardial infarction and death.
Prompt identification and management, including cardiac catheterization and percutaneous coronary intervention, are crucial.
This case highlights the importance of considering cardiac ischemia in patients with COVID-19 and respiratory distress, even with atypical presentations.